Listen to Base by Base podcast

467: Finding mutations carried by fewer than 1 in 100 cells	Base by Base	18:37
466: A quieter MECP2 switch and the male bias in autism	Base by Base	18:45
465: When a lysosomal storage gene shows up only in the retina	Base by Base	20:03
464: Burning fat while sparing muscle on GLP-1 drugs, in mice	Base by Base	18:20
463: Why brain traits leave faint, common genetic signals	Base by Base	18:21
462: A vessel gene tied to AMD dims low-light vision in mice	Base by Base	20:10
461: Adult Ank3 loss quiets neurons and lowers a myelin protein	Base by Base	24:55
460: The lupus variant that also sharpens antiviral defense	Base by Base	24:13
459: Cerebral palsy genetics: 515 candidate genes, evidence for 89	Base by Base	24:06
458: Somatic or inherited? Reading TP53 risk from shared DNA	Base by Base	25:09
457: A deletion that raises Alzheimer risk, a duplication that lowers it	Base by Base	24:15
456: Beyond exons: where heritability hides as traits get more polygenic	Base by Base	45:46
455: Agentic genomics: the bottleneck moves from code to judgment	Base by Base	13:44
454: Efavirenz retarda a doença priônica mexendo no colesterol do cérebro [PT]	Base by Base	17:13
453: Efavirenz slows sCJD progression by reshaping brain cholesterol	Base by Base	20:56
452: Reduzir a PrP funciona em todas as linhagens [PT]	Base by Base	28:42
451: Prion protein lowering is disease-modifying across stages and strains	Base by Base	24:36
450: ASOs que reduzem PrP prolongam a sobrevida [PT]	Base by Base	24:57
449: siRNA divalente para doença priônica [PT]	Base by Base	28:46
448: PrP‑lowering ASOs prolong survival in prion‑infected mice	Base by Base	25:16
447: Divalent siRNA for prion disease	Base by Base	23:33
446: Cilia, Synuclein, and Survival: G51D Mice Reveal a Shared Parkinson’s Pathway	Base by Base	28:38
445: Why Thymine Survived the UV: Photodamage Pathways Explained	Base by Base	26:55
444: Many-eyes or Sentinels? How Cost Curvature Shapes Collective Vigilance	Base by Base	24:40
443: 5D‑ASO boosts exon 51 skipping and restores dystrophin in DMD models	Base by Base	19:35
442: When pumps go missing: Ca2+ control of PMCA2 in Tmc1 deafness mutants	Base by Base	22:57
441: Evolutionary mapping of Cav1.3 functional sites	Base by Base	24:01
440: DENV-4: Suppressing DNA Repair and Causing Genome Damage	Base by Base	23:41
439: Coembedding Sequence and Structure: CLSS Maps the Protein Universe	Base by Base	23:08
438: Mapping AIRE: a proactive atlas of 9,790 missense variants	Base by Base	24:02
437: Cell villages and Dirichlet modeling map human cell fitness genetics	Base by Base	28:03
436: KIAP4 and the ARND family: building the Leishmania adhesion plaque	Base by Base	24:51
435: E. coli TGT binds two tRNAs — cryo-EM reveals dual engagement	Base by Base	19:03
434: High‑coverage genomes recast Japan's prehistoric demography	Base by Base	27:07
433: Lactate, HSP90α and the Mitochondrial Switch	Base by Base	23:55
432: Echovirus 18: Capsid opening releases the genome	Base by Base	18:29
431: KIAP4 and the ARND family: essential proteins for Leishmania–sand fly adhesion	Base by Base	21:33
430: Proterozoic Rise: Steady Diversification of Crown Eukaryotes	Base by Base	25:20
429: Validating the EAGL genetic literacy measure	Base by Base	23:49
428: Genetic regulation of plasma metabolites in people with HIV	Base by Base	28:03

467: Finding mutations carried by fewer than 1 in 100 cells

Base by Base

18:37

466: A quieter MECP2 switch and the male bias in autism

Base by Base

18:45

465: When a lysosomal storage gene shows up only in the retina

Base by Base

20:03

464: Burning fat while sparing muscle on GLP-1 drugs, in mice

Base by Base

18:20