Base by Base

Total duration:14 h 38 min
313: Integrating Polygenic Risk Scores and Social Determinants of Health across Populations
Base by Base
24:46
312: Mfsd2a transports LPC to maintain epidermal linoleate pools and desquamation
Base by Base
14:53
311: mtG3PDH (GPO1) loss in Drosophila impairs mitochondrial ATP/O, O2 consumption, and ROS
Base by Base
42:24
310: Infant gut microbiota restoration — maternal FMT, Bifidobacterium and Bacteroides recovery after C‑section
Base by Base
49:10
309: LASI-DAD 2,680-sample WGS panel boosts LD maps, imputation, and PRS in Indian genomes
Base by Base
23:42
308: PANDORA-seq reveals conserved rsRNA length shift and tsRNA/rsRNA aging cliff in mouse and human sperm
Base by Base
22:25
307: SNIPE membrane nuclease cleaves phage λ DNA during ManYZ-mediated genome injection in Escherichia coli
Base by Base
27:44
306: SAXO6 loss-of-function in photoreceptor cilia links a microtubule inner protein to late-onset retinal dystrophy
Base by Base
25:09
305: Human cis-regulatory variants dissected by MPRA at single-nucleotide resolution
Base by Base
22:24
304: Patrilineal Y‑chromosome drive in a Utah pedigree (67% male offspring)
Base by Base
18:13
303: Short-read sequencing and genome skimming for biodiversity monitoring and phylogenomics
Base by Base
29:00
302 auf Deutsch: SMN1/SMN2-Spleißen und Mechanismen im letzten Exon — Hommage an Brunhilde Wirth
Base by Base
13:58
302: SMN1/SMN2 splicing and last-exon mechanisms — Tribute to Brunhilde Wirth
Base by Base
24:12
301: Biobank Mendelian randomization prioritizes 6,447 genes and nominates ANXA2 for dyslipidemia
Base by Base
20:53
300: Population-scale WGS links MHC class II antigen presentation to persistent Epstein–Barr virus (EBV) DNA
Base by Base
21:48
299: UFM1 loss and R81C mutation disrupt neuronal translation, ER stress, and synaptogenesis
Base by Base
21:15
298: Bi-allelic FSD1L variants in retinitis pigmentosa implicate photoreceptor axoneme
Base by Base
20:16
297: Bi-allelic FSD1L variants disrupt mitotic spindle and ciliogenesis in an L1-like neurodevelopmental disorder
Base by Base
21:27
296: snaR-A ncRNA antagonizes U2 snRNP SF3B2 to drive intron retention in human cells
Base by Base
20:38
295: CFTR deltaF508 and CF-risk variants protect against IBD in large exome study
Base by Base
28:25
294: Alternative splicing, exonization and lineage-specific isoforms: PTBP1, MAPT and TE-derived exons in mammalian evolution
Base by Base
36:58
293: IndeLLM (ESM2) zero-shot scoring and Siamese transfer learning for in-frame indel prediction (MCC 0.77)
Base by Base
17:53
292: INS R6C signal-peptide defect reduces preproinsulin ER translocation in iPSC-derived βcells
Base by Base
17:09
291: Dated gene duplications show Asgard archaeal host complexity before mitochondrial endosymbiosis
Base by Base
06:39
290: SMN1 p.Arg288AlafsTer5 exon 7 deletions evade PCR newborn screening yet yield functional SMN isoform
Base by Base
19:14
290 auf Deutsch: SMN1-Exon-7-Deletionen p.Arg288AlafsTer5 entgehen dem PCR-Neugeborenenscreening und erzeugen dennoch eine funktionelle SMN-Isoform
Base by Base
25:20
289: MinION detection of chimeric reads in murine Ifna/Ifnb and Actb amplicons
Base by Base
16:18
288: Cryo-EM of rat cerebellar α1/α6 GABAA receptors reveals PZ‑II‑029 binding and β-α-β-α-γ assemblies
Base by Base
16:55
287: EPOP and MTF2 modulate PRC2 H3K27me3 deposition via GA- and GCN-sequence specificity
Base by Base
18:47
286: Deep mutational scanning of Nipah virus fusion protein F reveals functional and antigenic constraints
Base by Base
19:48
285: ESBX (Tb927.3.1660) integrates ESB RNA Pol I localization with BES activation and VSG repression in Trypanosoma brucei
Base by Base
19:39
284: FES, VSMC behavior and pleiotropic vascular genes identified by integrative functional genomics
Base by Base
17:41
283: Confidence in genetic knowledge drives Familiarity, Knowledge, and Skills in US GALS samples
Base by Base
18:17
282: Gene-specific variance-control corrects polygenicity-driven inflation in TWAS
Base by Base
20:00
281: Variant-level mapping of ACTB and ACTG1 defines eight non-muscle actinopathies and links BWCFF to actin polymerization defects
Base by Base
20:37
280: SCD, FADS and a 3p25.2 (PPARG) locus shape fatty acid composition in human subcutaneous adipose tissue
Base by Base
17:04
279: Against the Uncritical Adoption of AI in Universities: LLMs, Chatbots, and Academic Integrity (Guest et al.)
Base by Base
20:15
278: Illumina, Grail and FTC scrutiny of vertical mergers in human genetic technologies
Base by Base
19:06
277: MDGA2 homozygous loss-of-function variants in developmental and epileptic encephalopathy
Base by Base
18:27
276: AlphaGenome: 1-Mb multimodal deep model predicts regulatory variant effects including splicing and TAL1 mechanisms
Base by Base
19:40